CSB328H1 Midterm: TT1 review
6 Mar 2017
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Lecture 1 - september 12th 2016 - introduction to development and model organisms. Chapter 1: p1-3: intro and questions; p15-17: 4 principles of ke von baer. Developmental process - development never stops, and brain develops continuously: child: growth, changes in body proportions, brain development, puberty: changes in the production of sex hormones. Changes in body shape, new organs (breast), specific hair aireas, increase in muscles mass. Production of mature germ cells (differentiation of egg and sperm: young adults: homeostasis through regeneration of tissues (stem cells, senescence: menopause, shift from muscle to fat production and cancer is a developmental disease. Human embryogenesis: week 1-9 embryogenesis (carnegie stages into 23 stages, week 9-40 fetal development. Model organisms allow us to study embryogenesis: life observation of development: follow cell division, cell mvmt, cell differentiation, experiments. Physical manipulations - cell ablation, tissue transplantation, injections. Genetic manipulations - change activity of developmental genes: properties.
