IMM250H1 Study Guide - Quiz Guide: Weak Interaction, Hospital-Acquired Infection, Vaccinia

76 views9 pages
23 Feb 2013

Document Summary

Mucosa body surfaces potentially exposed to microbes. Physical barriers: anatomical barriers, mechanical factors, chemical factors, biological factors. Blood-borne factors: humoral components, complement, coagulation system, cytokines. Innate cells defenders : cellular components, neutrophils, epithelial cells, monocytes and macrophages, nk cells, eosinophils. Removal of particles including microorganisms by rapid passage of air over cilia in nasopharynx. High turnover rates, allows skin cells to slough off at high rates - protective mechanism because if pathogen stuck on skin it will be sloughed off in a few days. Mechanical factors: cell type: squamous epithelium, physical barrier, desquamation. Prevents attachment: component: hcl (parietal cells in stomach) Kill bacteria: component: tears and saliva, lysozyme and phospholipase a. Kill bacteria by dissolving cell wall: component: antimicrobial peptides, defensins (respiratory & gi tract, antimicrobial. Antimicrobial molecules that can poke holes in bacteria and kill them: component: surfactants (lung, opsonin (enhances uptake by phagocytes) Coat bacteria particles and are more easily recognized by innate system.

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers

Related Documents