IMM250H1 Study Guide - Final Guide: Helicobacter Pylori, Gut Flora, Crystal Violet

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3 Apr 2018
Hematopoietic stem cell: all immune cells are produced here.
Common Lymphoid Precursor: CLP is responsible for cells of adaptive immunity;
T cells, B cells and NK cells
Common Myeloid Precursor: CMP is responsible for cells of innate immunity;
macrophage, monocytes, neutrophils and granulocytes
Germ theory of disease: theory that diseases are caused by microorganisms
Side-Chain Theory: By Paul Ehlrich; Lock and key model
Clonal Selection Hypothesis: each cell expresses an antibody that is specific
for each antigen
Helicobacter pylori: bacterium with polar flagella found to be the cause of
gastric ulcers
Superbugs: antigens that are no longer resistant to bacteria
E Coli has gram negative cell wall and can be stained red
Staphylococcus has gram positive cell wall and can be seen crystal violet
NFkB is the master regulator of inflammation and also controls the production
of soluble mediators of innate immunity.
Firmicutes and Bacteroidetes are the two main type of divisions of bacteria in
the gut microbiota
TRR: Toll IL1 Receptor involved in signalling inside the cell
The binding of two TRR activates the signalling
Autocrine effect: when cytokines bind to the same cell that released them.
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