IMM340H1- Final Exam Guide - Comprehensive Notes for the exam ( 49 pages long!)
Document Summary
The immune system is composed of organs of cells and tissues. Bone marrow is where immune system cells originate. The cells sense and express molecules like immune receptors and cytotoxic molecule. s. Cytokines are secreted from cells to communicate with other cells, they can induce differentiation and many other things. Chemokines are chemo attractants, they attract cells to a specific location and this is how leukocytes are driven towards a specific location. Pathingen life cycles are very fast, so they can evolve quickly. The immune system responds differently to different stimuli. Not everythi(cid:374)g that"s (cid:374)o(cid:374)self is da(cid:374)gerous to our (cid:271)ody. The (cid:373)ajority of the i(cid:374)testi(cid:374)al (cid:373)i(cid:272)ro(cid:271)iota is good, they are beneficial. Cencer cells are self cells that are normally programmed but because of genetic alteration, they cause issues. Viruses hide themselfes from the immune system by downregulate the expression of surface proteins. The molecules the innate immune system identifies are important to the life cycle of the pathogen.
