PSL300H1 Study Guide - Midterm Guide: Protein Kinase A, Adenylyl Cyclase, Thyrotropin Receptor
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Case study: maintenance of blood pressure knowledge of the physiology of b. p. control allows treatments: (cid:3381) drugs (cid:3381) direct baroreceptor s(cid:415)(cid:373)(cid:437)(cid:367)a(cid:415)on. Cause: only makes proinsulin (cid:0) insulin f"n decline, overprodu(cid:272)(cid:415)on due to(cid:3)(cid:400)(cid:415)mulus of high [gluc: can check by tes(cid:415)ng for c-pep(cid:415)des in blood, types of hormones. Page 1 of 16 (cid:3381) (cid:3381) (cid:0) fsh glycosylated: water soluble (dissolved in plasma) i. e. , don"t need carrier (cid:3381) Short half-life in plasma (b/c unprotected: bind to membrane receptors (cid:3381) (cid:302)nal products cleaved during processing (cid:0) Receptors & signaling: how do hormones signal, receptors bind to receptor (cid:0) conformational change and altered a(cid:272)(cid:415)vity of receptor (cid:0) alter ac(cid:415)vity of intracellular signaling pathways (cid:0) change in synthesis of target proteins and/or modi(cid:302)(cid:272)(cid:258)(cid:415)on of exis(cid:415)ng proteins. Epinephrine (cid:0) (cid:1112)(cid:3)(cid:336)(cid:367)ycogenolysis,(cid:3)(cid:1113) glycogenesis (i. e. , more break-down, less synthesis) Ecf 0. 1: exchanges calcium w/ bone and cells (analogous to a bu(cid:299)er )
