PSL300H1 Study Guide - Comprehensive Final Exam Guide - Pituitary Gland, Hypothalamus, Hormone
Document Summary
Homeostasis: the process of maintaining a constant internal environment despite. Local signalling: molecule released by cell that acts on itself, molecule releases works on nearby cell, hormone released into blood stream, hormone released into duct. Removing pancreas: extreme weightless and water loss, body inability to absorb glucose because of no insulin; gets excreted, excessive urination, can be reversed by transplanting pancreas/insulin injections in intervals. If an enzyme that converts one hormone to another is deficient, the excess will be converted to a different steroid hormone: e. g. Integrin receptor: becomes dimerized, requires cofactors, gas - stimulatory, gai inhibitory (adenyl cyclase, gaq - activates phospholipase c, adenyl cyclase, phosolipase c, guanylyl cyclase. G protein coupled receptor targets: signal amplification/efficiency. Ligand binding opens or closes channel: changes electrical properties of cell, hyperpolarization, depolarization. Liver glucose release: fat fatty acid release, muscle/blood vessels less vasoconstriction, hormones: norepinephrine and epinephrine.
