Biology 1001A Study Guide - Final Guide: Allele Frequency, Genotype Frequency, Melanocortin 1 Receptor

• School: Western University
• Department: Biology
• Course: Biology 1001A
• Professor: Tom Haffie

Document Summary

General pathway of eukaryotic membrane protein production: dna is translated to rna, rna transcribes proteins, proteins are passed through rough er through vesicles to golgi body, transported from golgi (cid:271)ody to (cid:272)ell"s su(cid:396)fa(cid:272)e. General physiology of skin/hair pigmentation: ski(cid:374) (cid:272)ells do(cid:374)"t (cid:373)ake pig(cid:373)e(cid:374)t, (cid:373)ela(cid:374)o(cid:272)ytes (cid:373)ake pig(cid:373)e(cid:374)t, pigment (melanin) is then exported to skin cells. Combination of black and red in the same cell -> brown. Characteristics of dominant alleles: there is no connection between dominance and goodness, dominant alleles do not inhibit the other allele, they just mask them. Which allele in a heterozygote is dominant, given the biochemical mechanism of action of allele products. Whether or not the dominance status of an allele affects its frequency over time in a population. I(cid:374) the a(cid:271)se(cid:374)(cid:272)e of sele(cid:272)tio(cid:374), a(cid:374) allele (cid:271)ei(cid:374)g do(cid:373)i(cid:374)a(cid:374)t o(cid:396) (cid:396)e(cid:272)essi(cid:448)e does(cid:374)"t affe(cid:272)t f(cid:396)e(cid:395)ue(cid:374)(cid:272)y. Function of black, brown and red mc1r alleles as described in simutext: gene mc1r.