Biology 1001A Study Guide - Final Guide: Color Blindness, Indel, Xyy Syndrome
4 Apr 2017
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Document Summary
Snps come from a failure of proofreading to a failure of mismatch repair. Sometimes 5-bromouracil gets incorporated into dna instead of thymine. Thymine and uracil are tautomerically and relatively stable. Equilibria are in favour of the usual tautomer. Not inventing a new mechanism, but enhancing an already natural mechanism. This is an example of chemical mutagens that increases mutation frequency. One or two base pairs missing or added. Many of the differences between humans are just that: missing or extra base pairs in certain spots. Cycle 4 - recombination and meiosis page 1. Because there are so many t"s in a row, the new strand can slip (0:20s) An extra t has been added onto the strand. Can happen in the new strand or in the template strand (0:48) Slippage on new strand adds an extra base pair (1:05) Slippage on the old strand loses a base pair (1:14)
