Kinesiology 4432A/B Study Guide - Final Guide: Phenylephrine, Norepinephrine Transporter, Skeletal Muscle
14 Apr 2018
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An attenuation of the vascular response to an augmented sympathetic outflow. The functional reduction of sympathetic vasoconstriction in contracting skeletal muscle. We have multiple layers of control to optimize the response. I(cid:374)tegrates (cid:862)systemic(cid:863) sy(cid:373)patheti(cid:272) a(cid:272)ti(cid:448)atio(cid:374) (cid:449)ith (cid:862)local(cid:863) fa(cid:272)tors to regulate blood pressure and local muscle perfusion. The systemic part is the neural part it is the reduction in parasympathetic of the heart; it is the increase in sympathetic outflow to the muscle or whatever neural target it is. Norepinephrine transporter it takes up norepinephrine and then repackages it; ne is taken away from neuro-vascular cleft this is a form of local control. It is a balance between constriction and dilation. Vasodilation happens when you exercise, levels of data which increases conductance. At steady state of exercise, you infuse a drug called phenylephrine (alpha 1 agonist) this drug causes vasoconstriction do you get when you infuse phenylephrine; the.
