Kinesiology 4432A/B Study Guide - Final Guide: White Matter, Parenchyma, Neurotrophic Factors

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Impact of long term high level endurance training on brain structure: working on healthy people and see if exercise can attenuate the negative changes in the brain from occurring as they get older. Hypothesis: long term high-intensity aerobic exercise training exerts a beneficial influence on cortical and subcortical mass (would too much be bad for you?) The differences between the masters athletes and control people is a wide spread effect (exercise impacts a lot of regions of our cortex) In all of the regions of interest, all of these were significantly greater in our master athletes than in our control. As get older, the master athletes may still have a little bit of the decline in the neural tissue, but they are still way higher than the control: hence, they have a preservation as they get older. For the subcortical region, there was not much difference between the two groups (masters and control)

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