Microbiology and Immunology 2500A/B Study Guide - Warm Compress, Coagulase, Hair Follicle
6 Jan 2013
School
Department
Professor
Document Summary
Facultative anaerobe (can use o but doesn"t need it) 2 types- coagulase test- snowflake like clots. Coagulase -: s. epidermidis, s. saprophticus, many others: aureus: Carriers- greater risk of infection, but better prognosis (baseline immunity) Spread by direct or indirect contact- fomites (towels, razors etc) Uses adhesins- to bind host tissue (fibronectin, collagen, ebp), imp. in endocarditis. Pyogenic (pus- producing) infections pus= dead nuetrophils. Hallmark = abscess (heat, red, swollen, pus) Abcess- mostly on skin, can spread to any organ. Do not heal themselves rewuire drainage, anitbiotics. Because many vf"s all of them regulated expression (surface or secreted when needed) Surface vf- during exponential growth- for colonization. Secreted vf- during stationary phase- for invasion/spread. Vf"s- immune invasion mechanisms: protein a: on surface, binds fc region of igg that the neutrophil fc receptor is supposed to bind, toxins kill leukocytes: cytolytic, actual targets are wbc, but can lyse rbc, so are called.
