[3820A] - Final Exam Guide - Ultimate 66 pages long Study Guide!

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Protect against microorganisms with potential to cause infectious disease called pathogenic microorganisms or pathogens. Bacteria cause the most human infections globally, -> fungi ->worms -> viruses - Less developed countries are more affected by fungi and worms (why numbers are so high) Influenza: hiv/aids, hpv, hep b, rhinovirus, e. coli, staphylococcus aureus, clostridium difficile, streptococcus pneumoniae. Immune system has to decide if something is a threat. External threat allergy, environment, your immune system can get it wrong (you get sick) Cancer avoids apoptosis and uncontrolled cell growth, oncogenes make them resist apoptosis and therefore they grow (tumours) Apoptosis: cells become damaged or worn out, programmed cell death. Autoimmune: own immune system attacks own cells (type 1 diabetes, t cells attack) Microorganisms reproduce and evolve quickly, they mature and mutate quickly it"s up to our body to decide if it"s a threat or not. Bacteria replicate by splitting in two, immune system needs to try to keep up.