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Reproductive Physiology I.docx

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Department
Physiology
Course
Physiology 3120
Professor
Tom Stavraky
Semester
Fall

Description
DrRegnaultReproductionPhysiology3120Male ReproductionSpermatogenesismaturationofsperminthereproductivetractSteroidogenesischemistryandsecretionofsteroidhormonesSpermatogenesisSertolicellsstimulatedbyFSHLeydigcellsstimulatedbyLHLocationofSpermatogenesisSpermatidsbasolateralmembraneluminalmembranethroughthesertolicellsLeydigcellssurroundtheSertolicellsBloodTestisBarrierAboveundergoingmitosisBelowunzipswhenspermatidsbegindifferentiationfromdiploidtohaploid8representsatightjunctionthebloodtestesbarrierformedbetweenadjacentSertolicellsImportantindiseaseandinfectioncanbreakdownBloodtestesbarrierprotectsimmunesystemfromforeignsubstancesSpermatogoniadividebymitosisordifferentiateintospermatocytesThewallsofthetubulesconsistofdiploidspermatogoniaMeiosisofeachprimaryspermatocyteproduces4haploidspermatidsThenthespermatidsdifferentiatematureintospermProcessofContinuousGermCellDifferentiationtoProduceSpermatozoaSwitchedonatpubertyEntireprocessoccursinseminiferoustubulesSertolicellsSpermatogoniacellsundergomitoticdivisionsprovidingaconstantcourseofcellsforsubsequentmeioticdivisionsfromstemcellsforgameteproductionSpermatocytescellsintheprocessofbecomingspermGermcellsarealwaysincontactwithSertolicellsExtraInanygivensectionofthetubulespermatogenesisproceedsinaregularsequenceEntireprocesstakesabout64daysbloodtestesbarrierlumenThenormalhumanmaleproduces30100millionspermday
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