Physiology 2130 Study Guide - Final Guide: Endoplasmic Reticulum, Myofilament, Skeletal Muscle

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Skeletal muscle structure a whole muscle, such as the bicep muscle, is made up of bundles of fascicles , and each fascicle contains bundles of muscle cells (which are also called muscle fibres ) Within each muscle cell, there are long cylindrical structures called myofibrils running the length of the muscle cell/fibre. Myofibrils are made up of myofilaments , which contain the proteins responsible for the actual muscle contractiontwo types of myofilaments: thick and thin myofilaments. G-actin - a globular protein which, when linked to other. G-actin molecules, forms a two-stranded alpha-helical chaineach actin molecule contains a myosin binding site , which are partially covered up in a relaxed muscle. Troponin - in the relaxed muscle, troponin is attached to the tropomyosin and actin in which a way that it holds the tropomyosin molecule over the myosin binding sites on the actin.

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