Psychology 2032A/B Study Guide - Quiz Guide: Electrodermal Activity, Autonomic Nervous System, Behaviorism

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The Neuroendocrine System
Hypothalamic-pituitary-adrenal axis
(
HPA
) = central to the body’s response to
stress, and stress
figures prominently in many psyc disorders
Hypothalamus releases corticotropin-releasing factor (CRF) when faced with
threat
CRF communicates with the pituitary gland, releases hormone that travels to
adrenal gland
Adrenal cortex promotes the release of hormone cortisol the stress hormone
o Takes 20-40 minutes for cortisol release to peak
o Takes up to an hour for cortisol levels to return to baseline
Autonomic nervous system
(
ANS
) = operates very quickly, without our awareness,
beyond voluntary
control
o Innervates the endocrine glands, the hearth, and smooth muscles
o
1)
Sympathetic NS
= prepares body for fight/flight (heart rate,
dilates pupils, inhibits
intestinal activity, increases electrodermal
activity)
o 2) Parasympathetic NS = helps calm down the body
o
Involved in anxiety
disorders (panic, PTSD)
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Psychoneuroimmunology = studies how psychological factors impact the
immune system
Immune system contains many cells and proteins that respond when the body is
infected/invaded
Natural immunity
= body’s first and quickest line of defense
against infections
microorganisms/invaders *releases
cells on invaders to destroy them
o Results in inflammation/swelling
o Cytokines = help initiate bodily responses to infection (fatigue, fever,
activation of HPA axis)
Release of cytokines stimulated by activation of macrophages (cell
released)
Specific immunity
= cells respond more slowly to infection (lymphocytes
t-
helper and b cells),
involved in responding to specific pathogens or invading
agents
o T-helper cells promote the release of cytokines
o B cells release antibodies
Stress directly effects the immune system (prenatal stress can even affect her
offspring)
Interlukin-6
= cytokine that promotes inflammation in response to infection,
linked to human
diseases and psyc disorders (MDD)
Exposure to stress also slows process of wound healing
Risk of harmful immune response to stress
increases with age
Neuroscience Approaches to
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