BIOL 1000 Study Guide - Final Guide: Peptide, Endergonic Reaction, Meiosis

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Prophase: dna twins condense and are called sister chromatid, each chromosome is a sister chromatid, nucleolus disappears, mitotic spindle fibers form from centrosomes, composed of microtubules, centrioles are at centre of centrosomes, centriole duplicates and move to opposite ends of nucleus. Telophase: chromosomes de condense, nuclear envelope forms around them, rna transcription resumes, mitotic spindle completely gone, cytokinesis happens now in most cells and ends at start of g1, cytokinesis is division of cytoplasm, animal cells: contractile ring with microfilaments(actin, myosin, animal cells: cleavage furrow develops between cells and deepens until there are. 3 major checkpoints in cell cycle: checks for right environment, lack of damage and all processes complete, cyclin dependent kinases regulate cell cycle, phosphorylates and activates proteins responsible for transitions, cdks are only activated when cyclin proteins bind to them, cylin in blocked by proteins until needed, problems with regulation system lead to cancer, can break and spread.

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