CHEM 4021 Final: CHEM 4021 notes 2013

• School: York University
• Department: Chemistry
• Course: CHEM 4021
• Professor: Art Orellana

Document Summary

Part 1 concepts: synthetic organic chemistry - introduction, development of a synthesis plan, reactivity patterns and umpolung, practical considerations in synthesis, selectivity in organic synthesis, conformational analysis review, acidity of organic molecules: review. Part 2 reactions: enolate alkylations, the aldol reaction, allylation of aldehydes, additions to carbonyl electrophiles: reductions. 12 additions to carbonyl groups: carbon nucleophiles: protecting groups. 14 oxidations: c-o bonds: useful methods for the synthesis of double bonds part 1, useful methods for the synthesis of double bonds part 2, reduction of double bonds, oxidation of double bonds. Organic molecules can be quite complex in structure; as a consequence their synthesis from relatively simple and readily available materials can present a significant challenge. The selection below should give you an idea of the variety and complexity of target molecules. 2005, 7, 2989: l. comins et al. O mutoporin: s. panek et al, am. 2007, 119, 4796 bullvalene: yamamoto et al, am.