CRIM 2653 Study Guide - Quiz Guide: Aciclovir, Tizanidine, Finger Cot
6 May 2020
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Information to be discussed with patient: name, strength and dosage form of medication. Apply liberally: indication, instructions, side effects, management and monitoring. Used for the treatment of initial episodes of genital herpes simplex infections (i. e. cold sores). Therapy should begin as early as possible after start of infection. Acyclovir is highly specific for herpes simplex specified thymidine kinase. It gets phosphorylated to acyclovir diphosphate and triphosphate. Acyclovir triphosphate is both an inhibitor of, and a substrate for, herpesvirus-specified dna polymerase. This blocks viral dna synthesis, and suppresses the virus. It is a synthetic acyclic guanosine nucleoside analog. Apply liberally to the affected area 4 to 6 times daily for up to 10 days. A sufficient quantity of cream should be applied to adequately cover all lesions. A finger cot or rubber glove should be used while applying acyclovir cream, in order to prevent autoinoculation of other body sites or transmission of infection to other persons.
