KINE 4020 Final: MINERALS SUMMARY: Calcium, Iron, Iodine

• School: York University
• Department: Kinesiology & Health Science
• Course: KINE 4020
• Professor: Rolando Ceddia

Document Summary

Calcium bones and teeth (99%) & intra and extracellular uid (1%) Critical role in muscle contraction, transmission of nerve impulses. Better when < 500mg & consumed w food. Insoluble form from foods &supplements = must be. Absorption freed into ionized & soluble form to be absorbed. Free ca can bind to other constituents that limit bioavailability factors that limit bioavailability: Ber, phytic acid, oxalic acid, unabsorbed fa factors that enhance bioavailability. Pth activates osteoclasts = release ca from bone to blood. Cofactor for enz activation (gpcr for adenylate cyclase, protein kinases, ca/mg atpase) In small intestine (duodenum and proximal jejunum) via. Cat1, calbindin d9k & calcium atpase pump (vit d dependent) Parafollicular cells in thyroid gland release calcitonin to . Calcitonin: suppresses pth release & activity of osteoclasts calcitonin ca in blood. De ciency rickets, osteomalacia, osteoporosis, tetany, heart failure, convulsions. Regulates energy metabolism, protein synth, fetal brain & skeletal development. Iodide stored by being incorporated into thyroglobulin.