KINE 4020 Midterm: TEST3 VITAMINS SUMMARY
2 Apr 2016
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Adipose tissue for b-carotene (excess storage does not cause used by adipose tissue, muscle, liver toxicity because its precursor) Synthesis of rhodopsin & other light receptor pigments (prevent night blind) Retinol esteri ed to palmitate by lrat, incorporated into chylomicrons. Retinol transported to peripheral tissues by rbp. Do not require digestion to be absorbed by small intestine. Ca absorption by intestine & resorption from bones (w pth) Xerophtalmia (can"t see in dark/ produce tears), impaired growth, immunity, reproductive. Osteomalacia and/or osteoporosis beef, liver, dairy, chicken, egg yolk, milk spinach, carrots, mango men > women endogenous prod can fully supply requirements egg yolks, fatty sh aged adults > adults. Light hits retina: rhodopsin cleaved into opsin and cis-retinal. Non-genomic effects: calcitriol binds marrs protein on selected tissue and ca uptake. Genomic effects: calcitriol binds rxr heterodimer in promoter regions of target genes and regulates expression of several proteins.
