KINE 4505 Midterm: SOMATOSENSORY SYSTEM
21 Oct 2016
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Alzheimer"s disease disorder in neurotransmitter metabolism disruptions in normal function of cholinergic neurons: somatosensory system somatosensation sensory info from skin and musculoskeletal system detects mechanical stimuli. 2 systems pain and temperature cutaneous and proprioception mechanoreceptors in skin meissner pacinian ruffini merkel free nerve endings meissner mechanoreceptors. 82 on non-hair skin (finger-tips) touch, pressure (dynamic) # meissner receptors decrease btwn 12-50 years old. Ra: low level frequency threshold good for vibration & texture pacinian mechanoreceptors. 10-15% of hand receptor to pressure and vibration. Sa: high frequency threshold respond to internal s, assist proprioception merkel mechanoreceptors in all skin, hair follicles touch, pressure. Sa: high frequency threshold good for sharp edges, shapes free nerve endings nociception, temperature. 86 stimuli applied to skin changes shape of r leads to receptor potential (mechanical channels) Ap travels down dorsal root ganglion sensory afferent to cns sensory neuron adaptation if stimulus persists w out change position or amplitude, intensity diminishes.
