MCELLBI 104 Final: MCB 104 Final Fall 2017 Study Guide

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All small, but vary widely in size. Electron: provides sub-cellular resolution, can reveal atomic structure of proteins. Create special environmental conditions (such as low ph) Amphiphatic = polar and nonpolar nature of phospholipids in particular polar hydrophilic heads that interact with the aqueous environment. Nonpolar hydrophobic tails that form a bilayer and hence a barrier that prevents polar molecules from entering the cell. The fluidity of the bilayer allows for the cell to form different shapes. Membrane component: cholesterol is interspersed in the lipid bilayer and supplies rigidity and mechanical stability . At low temperatures, cholesterol increases membrane fluidity because it disrupts the packing of fatty acid tails. At high temperatures, cholesterol decreases membrane fluidity because it blocks surrounding fatty acids from moving laterally. Cholesterol serves as a stabilizer, keeping the level of fluidity constant at high. Hormone precursor = cholesterol is converted into steroid hormones like progesterone and low temps. and testosterone.

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