BIOL 401 Study Guide - Final Guide: Proline, Affinity Chromatography, Antibody
Document Summary
First we discussed different types of genes and dna. Single-copy functional genes give rise to mrna, trna, and rrna. Repetitive dna form gene families (ancestral gene and mutated duplicate) and functional sequences through multiple copies of genes. What"s interesting is that the cell will keep one copy of the duplicated gene, but mutate the other. An example of a gene family is histones. Furthermore, coding sequences further break down into dispersed gene families (genes are spread out along one or more chromosomes) and tandem gene families (genes sitting right next to each other). On the contrary, repetitive dna also have sequences with no known function. These include repeats in the centrometic heterochromatin, variable number tandem repeats (address later), and transposed sequences, which include transposons and retro-transposons, and make up 45% of our genome. We also have spacer dna, which has no known function. Finally we have structural genes, which assemble the genome.