CAS PS 333 Study Guide - Quiz Guide: Hypokinesia, Striatum, Cell Nucleus

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Quiz 1
1. What is time course
a. Onset + duration
2. chose the curve with the lowest ed 50
a. One shifted most left?
3. higher ti is safer drug
4. which graph is p.o
a. Long duration and slow onset
5. which graph has fastest onset and briefest duration
a. Steepest slope
6. calculate the ti from the two graphs
a. LD50/ED50
7. which graph is therapeutic window
a. Is this the one with the wavy curves with the straight line across
b. I think it’s just two horizontal lines, like across a graph
c. Isnt that when the therapeutic window collapses
d. It should be the same thing just a wider gap
8. 4 fundamental phenomena of pharmacokinetics
a. Absorption, metabolism, distribution excretion
Quiz 2
1. 6 types of drugs
a. Antagonist, direct agonist, releasers, reuptake inhibitors, precursors,enzyme
inhibitors
2. 4 of these are classified as indirect agonists
3. mechanisms of inactivation of nt in synapse is reuptake into presynaptic neuron and
degradation of nt
Quiz 3
1. 2 most common opiod analgesics
a. Hydrocodone and oxycodone
2. cross tolerance
3. partial agonist have limited max effect
4. naloxone is put in suboxone for insuffiliation
5. 2 therapeutic effects of opiod antagonist
a. Rescue from overdose, prevent abuse of suboxone, other are rapid detox and
infertility in females.
6. fentanyl more potent than morphine
7. most widely prescribed drug, generic name, behavioral class, pharmacodynamic class
a. Vicodin, hydroxodon, analgesic, mu opiod direct agonist.
qUIZ 4
1. l dopa is a precursor
2. l dopa is a indirect dopamine agonist
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