BIOE-2010 Study Guide - Final Guide: Biocompatibility, Rheumatoid Arthritis, B Cell
4 Apr 2016
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Allogeneic: antigen- presenting cells (apcs, autologous, b cells, bioactive. Study online at quizlet. com/_2297i2 grafts of another human"s tissue generally rejected over 1-2 weeks: b-cells and t-cells need time to graft & bond (kidney and liver usually take longer) Immune recognition of blood group proteins (a,b,o) and mhc cell surface proteins. If immune suppressive drugs are used, it can be controlled for organ transplantation--> causes vulnerability to infection (viruses) and cancer (uncommon) macrophages dendritic cells lymph nodes (sites of b and t cells and lymphocytes) The cell presents the antigen & mhc on surface grafts of patient"s own tissue no immune rejection complications immune system does not recognize self proteins (unless autoimmune disease) Produce antibodies that bond to the foreign protein on the bacteria cell. Macrophages bind to antibody bonded to foreign protein to perform phagocytosis. Each b cell produces 1 antibody (immunoglobulins igg) Library/portfolio of b-cells: depending on pathogen, a b-cell/antibody that recognizes it is selected.
