ANP 1107 Lecture Notes - Lecture 11: Regulatory T Cell, Antigen-Presenting Cell, Bone Marrow

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1107
• Professor: Joanna Komorowski

Document Summary

Immunity part2: adaptive defense system: third line defense: attack specific unknown invaders take slow reaction to response. Very specific response to antigen for bacteria, virus, cancer cells. Adaptive memory allows quick response due to previous exposure. Gives the immunity distinguishing between self and non-self, only immune reaction to the unknown substance. T cells as injecting enzymes for destroying harmful foreign organisms. Antibody-mediated immunity (humoral)- specificity depends on b cells and antibodies. Cell-mediated immunity (cellular) - specificity depends on t cells and their ability to kill antigens directly or indirectly. Antigen: a substance that can mobilize the adaptive defenses & immune response- from the body perceiving it as foreign. Endogenous antigens: (inside the body) protein expressed on the outer surfaces of cancer cells, virus-infected cells, bacteria infected cells, etc specific recognition by cytotoxic t cells + memory t cells. Exogenous antigens: (outside the body) bacteria, toxins and free viruses specific recognition by b cells + memory cells.