AS.020.305 Midterm: cell bio final study sheet (dragged) 1
Document Summary
Cellacycle*control*can*be*dissected*genetically*by*analysis*of*yeast*mutants: yeasts are tiny, single-celled fungi, with a cell-cycle control system remarkably similar to our own. Two species are generally used in studies of the cell cycle. Schizosaccharomyces pombe and the budding yeast saccharomyces cerevisiae: many important discoveries about cell-cycle control have come from systematic searches for mutations in yeasts that inactivate genes encoding essential components of the cell-cycle control system. The genes affected by some of these mutations are known as cell division-cycle genes, or cdc genes. Many of these mutations cause cells to arrest at a specific point in the cell cycle, suggesting that the normal gene product is required to get the cell past this point. Cell*cycle*control*can*be*studied*in*cultured*mammalian*cells: when cells from normal mammalian tissues are cultured in standard conditions, they often stop dividing after a limited number of division cycles.
