MICR 803 Study Guide - Quiz Guide: Sigma Factor, Consensus Sequence, Central Dogma Of Molecular Biology

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The central dogma of molecular biology describes the two-step process, transcription and translation, by which the information in genes flows into proteins: Operon: a set of genes transcribed under the control of an operator gene. Elongation: creation of the mrna transcript and addition of nucleotides. Termination: stopping transcription, sequence at the end of gene releases the rna polymerase. Promoter is an on and off switch for transcription not part of the mrna (upstream of the coding strand) Rna polymerase: holoenzyme: the core and sigma factor. Two alpha subunits, beta, beta prime and omega subunit. Only the core is require for the elongation phase (not omega) The sigma factor is for initiating transcription: helps rna know where to start transcription. Regulons: operons that are regulated at same time by the same control proteins (the sigma factor) at different locations on the chromosome.

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