BIOL 2153 : FINAL EXAM Genetics
Document Summary
Prokaryotic gene regulation chapter 17 problems: 5, 7, 8, 10, 12, 22, and 29. Gene regulation: control of gene expression processes, transcriptional, binding of rna polymerase to promoter, release of the mrna at termination. Shift from transcriptional initiation to elongation: post-transcriptional, mrna stability, efficiency of ribosomes recognizing translational signals, polypeptide stability (post-translational, the key regulation step for most bacterial genes is: the binding of rna polymerase to dna promoter. Lactose utilization in e. coli: classic model for gene regulation: e. coli need sugar as a source of carbon and energy, adding lactose leads to a 1000-fold increase in protein synthesis. Induction: a specific molecule stimulates synthesis of a protein. *there is no inducer in position when lactose is not present: rna polymerase cannot move down the gene structural genes do not get transcribed. If lactose is present, allolactose binds repressor: conformational change in repressor (allosteric.
