CHEM 1000 Final: CHEM 1000 Mizzou Final Exam

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15 Feb 2019
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E5 practice: (32 points) circle the letter on the right that corresponds to the answer to each question. Ff: (a) (30 pts) provide the structure of the major organic products of the following reactions. Ch3oh (b) (8 pts) provide a brief explanation, with reference to a key mechanistic intermediate, for why the following chiral ketone undergoes racemization in the presence of base. O: (15 points) provide a sequence of reactions, showing the reagents and structures of all isolated synthetic intermediates, to prepare the following using 1-propanol and/or methanol as the source of all carbon atoms in the final product. Do not show mechanisms or the structures of reactive intermediates. Shorter, more efficient syntheses are preferred; overly long or inefficient sequences will lose some credit. O: (15 points) treatment of a mixture of acetone (2-propanone) and ethyl chloroacetate with base gives a product with (1h nmr data is provided below).

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