Ch. 16-17 Molecular Genetics (Exam 3).docx

5 Pages
79 Views
Unlock Document

Department
Biology
Course
BIOL 110
Professor
D R.J O H N P E L E S
Semester
Fall

Description
Biology 110 Dr. Peles Date: / / . Molecular Genetics: Chapter 16-17 I. Review of DNA Structure Nucleic Acid Structure A. Components of Nucleotide Structure 1. Phosphate group 2. Deoxyribose sugar 3. Nitrogenous base i. Adenine (A) ii. Thymine (T) iii. Guanine (G) iv. Cytosine (C) DNA Structure B. Complementary base pairing 1. A ↔ T 2. G ↔ C II. DNA Replication DNA Replication is Semi­Conservative DNA Replication ~ 1 ~ Biology 110 Dr. Peles Date: / / . DNA Replication in Prokaryotes DNA Replication in Eukaryotes III. Proteins Needed for DNA Synthesis A. DNA polymerase- Enzyme responsible for synthesis of DNA B. Helicase C. Single-stranded binding protein (SSBP) D. Topoisomerase E. Primase F. Telomerase IV. Characteristics of DNA Polymerase A. Can only add to an existing nucleotide strand B. Can only add nucleotides to the 3’ end of an existing nucleotide chain Directions of DNA Synthesis Discontinuous replication Continuous replication C. Leading strand 1. Helicase separates double helix ~ 2 ~ Biology 110 Dr. Peles Date: / / . 2. SSBP prevents strands from reattaching 3. Topoisomerase stabilizes molecule 4. Primase makes short RNA primer (3-6 nucleotides) 5. DNA polymerase begins adding to 3’ end Leading Strand Synthesis D. Lagging strand 1-3. Same as leading strand 4. Primase makes primers 5. DNA polymerase adds to 3’ end (pairing in opposite direction, creates Okazaki fragments) V. Chromosome Structure Chromosome Structure Chromatid (700 nm) Nucleosome 30-nm fiber (10 nm in diameter) DNA double helix (2 nm in diameter) Loopsffold Histone tailH1 Histones
More Less

Related notes for BIOL 110

Log In


OR

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit