BIOL 4376 Study Guide - Final Guide: Blood Sugar, Reference Range, Liver Disease
Document Summary
Regulates amount of h2o in urine as a result of antidiuretic hormone (adh), which facilitates h2o reabsorption. I. e. dehydration, collecting duct reabsorbs more water to help urine concentration. Serum creatinine (scr) - the worse the kidney function, the higher the scr excreted at a relatively constant rate. Made from metabolism of creatinine in skeletal muscle and dietary meat intake. Released into circulation at a constant rate. Freely filtered across glomerulus and excreted by kidneys; neither reabsorbed nor. Most important endogenous biomarker used for detection of kidney disease metabolized by kidney. Increased scr commonly caused by renal dysfunction (or increased protein diet) Decreased scr commonly caused by decrease in muscle mass (i. e. elderly, malnutrition) Blood urea nitrogen (bun) - acute kidney injury (aki) Description: test that measures amount of urea in blood. Protein metabolism amino acids metabolized to ammonia converted to urea in liver. Filtered and excreted by kidneys; about 40-50% of filtered urea is passively absorbed (mostly in proximal tubule)