NUR 326 Study Guide - Midterm Guide: B Cell, Superinfection, Dsl Filter

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Chronic months or years (ex: ra: swelling, pain, warmth, redness, five steps. H1 receptors in vascular smooth muscle; stimulation results in itching, pain, edema, vasodilation, bronchoconstriction. Systemic corticosteroids treat severe inflammation: naturally released from adrenal cortex, suppress histamine & prostaglandins, can inhibit immune system to reduce inflammation. Antipyretics goal is to lower body temp. while treating underlying cause which is usually infection. Immunomodulatory sti(cid:373)ulates o(cid:396) supp(cid:396)esses (cid:271)od(cid:455)"s defe(cid:374)ses. Innate (nonspecific) defenses first line: deny entrance of pathogens, skin, nk cells, phagocytes, complement system, fever, inf, inflammation, always the same response no matter what. Adaptive (specific) defenses second line: immune response, lymphocytes interact w/ antigens, 2 major divisions antibody-mediated (humoral) & cell- mediated. Cell-mediated immunity activation of specific t cells. Immunosuppressant i(cid:374)hi(cid:271)its pt"s i(cid:373)(cid:373)u(cid:374)e s(cid:455)ste(cid:373); fo(cid:396) se(cid:448)e(cid:396)e autoimmune disease; prevent tissue rejection following organ transplant. Calcineurin inhibitors bind to calcineurin and disrupt t cells; treats psoriasis.

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