NUR 326 Study Guide - Midterm Guide: Varicella Zoster Virus, Herpes Simplex Virus, Antiprotozoal
22 Aug 2016
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Antiviral; inhibits viral replication by suppressing synthesis of viral dna. Inhibitor (nrti); inhibits hiv replication by suppressing synthesis of viral dna. Reduce transmission rate of hiv from mom fetus. Infuse iv slowly to ensure adequate hydration. Prolonged therapy can lead to organ deformities, blood disorders, fat redistributed (lipodystrophy) Po; take up to 5x a day- shorter half life. Might potentiate anemia and bone marrow depression. High doses are taken only briefly leads to toxic level within parasite. Antiprotozoal; also has antibiotic activity against anaerobic bacteria. Ectoparasiticid es; toxic to mites, lice and their ova (also fleas and ticks) Temporary sensations of burning, numbness, and stinging. Residual activity up to 2 weeks after treatment. Category x- avoid pregnancy for 6 months after therapy. Caution in pregnancy, hepatic, cardiac, and renal insufficiency. Wear protective clothing (gloves, mask, apron) when preparing drug. Must be given iv or instilled into body cavity.
