BSCI 440 Study Guide - Midterm Guide: Intercostal Nerves, Intercostal Muscle, Tidal Volume

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Write out the reaction that generates hco3 and h+ from co2. Co2 + h2o h2co3 h+ + hco3- What is the chloride shift, and what role does it play in keeping the reaction that converts co2 to. It balances the charge and moves hco3 out into the plasma so that co2 can sintue to enter the cell and continue the rxn. Hb buffers protons to keep the ph from going too low; it decreases the saturation of o2 bc it decreases ph. Bc less o2 there you want to pick up co2 at tissues and drop at lungs, haldane effect. The hco3- comes into the rbc and the cl- leaves. Reverse of reaction at tissues, converted back into co2 (+h2o), very fast thanks to ca. Arterial po2 need to be below ~60mmhg before significant increase in ventilation not sensitive enough for normal range.

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