MIC 205A Study Guide - Quiz Guide: Cytotoxic T Cell, Natural Killer Cell, Coccidioides Immitis
30 Mar 2017
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Document Summary
When a pathogen enters the body it stimulates the innate immune system. Neutrophils are a type of white blood cells. Prr"s find pamp- pathogen associated molecular patterns. Pamps are typical patterns presents on pathogens cells. Cytokines are released to communicate with other cells. Complement cascade stimulates c5a, c3a and c3b. C5a is a chemotaxin helps with the adhesion of wbc. C5a and c3b act on mast and basophil cells cause release of histamine. Release of histamines is a part of inflammatory response which increases the permeability of capillaries to white blood cells. Complement cascades wants to get wbcs to the pathogen. C3b is an apopsonin attach to pathogen, allow varies phagocytes like macrophages to locate, attach, and engulf pathogen then eventually destroy it. If a pathogen enters a human cell stress signals are released from cell that activated natural killer cells. Natural killer cells will send chemical signals to destroy human cells that sends stress signal.
