BIO 110 Study Guide - Midterm Guide: Taq Polymerase, Lac Operon, X-Ray Crystallography
Document Summary
Bio exam 2 study guide (september 20 october 20) Antifreeze: hydrophilic, binds to water molecules and prevents more from adding on. Mucins: many configurations, forms many links (more links, more viscous, dimerization bonds binds proteins together head to tail, has a lot of cysteine. Hemoglobin: high and low affinity oxygen state (t and r) Six types: oxidoreductases catalyze redox rxns, transferases transfer chemical groups, hydrolases break chemical bonds with water, lyses break bonds with something other than water, ligases make connections. Lock and key is not accurate because enzyme changes structures as it binds, instead it is more like a baseball mitt which changes shape when gripping the ball (induced fit model. Koshland: protein becomes a better structure to fit the ligand, kd is the dissociation constant that determines substrate concentrate at 50% Irreversible inhibition is when inhibitor binds to enzyme covalently and prevents enzyme function completely.
