AH 3121 Study Guide - Midterm Guide: Macrophage, Innate Immune System, Lymph Node
Document Summary
Polyclonal activators of t cells include pha, super antigens, and antibodies against cd3 proteins. The immune response normally declines 1-2 weeks after infection is eradicated. Alum is the only adjuvant licensed for vaccine use in the usa. Hiv patients are prone to viral infections because a lack of cd4+ cells which help cd8+ cells kill infected cells. Cyclosporin is a drug that inhibits the activity of calcineurin, is an immunosuppressive agent, and prevents transplant and graft rejection. Th2 cells are involved in the stimulation of b cells to secrete ige antibodies. The formation of th2 cells is in response to parasitic infections. The formation of th1 cells is in response to bacterial infections. Memory t cells survive in the circulation, lymphoid tissue, and mucosal barriers. Il-2 is the cytokine secreted by and acting upon cd4+ t cells to stimulate cd4+ t cell proliferation. Interleukin-12 gamma functions in the activation of th1 cells.
