MCB 244 Study Guide - Midterm Guide: Bone Remodeling, Manitoba Highway 1, Calcitriol

• School: University of Illinois
• Department: Molecular and Cell Biology
• Course: MCB 244
• Professor: C Brown

Document Summary

=osteoclasts i. ii. iii. large , multinucleated phagocytic cells. Bone decreased: calcium, required for, muscle contraction initiation ii. iii. iv. Blood clotting: hormones that regulate blood calcium i. Calcitonin: least significant role, released from thyroid, response to high levels of blood calcium. 4: stimulates kidneys to increase loss of. Inhibit osteoclast activity calcium in urine which decreases blood calcium ii. Pth: secreted for pt glands, reduce calcium levels, accelerates conversion to calcitriol by kidney iii. Inactive form of vitamin d made by integument: stimulates absorption of calcium ions from small intestine into blood, made by kidneys, circulated in blood, pth increases, calcitriol increases, fractures i. Fracture hematoma occur, bleeding, blood clot formation initiated. Happens at ankle, affects both bones of the leg: comminuted fracture i. Shatter affected area into multiple pieces: transverse fracture i. Break a bone shaft across it long axis: spinal fractures i. Produced by twisting stresses the spread along the bone: colles fracture i.