BIOLOGY 141 Study Guide - Final Guide: Single-Nucleotide Polymorphism, Copy-Number Variation, Acute Myeloid Leukemia

• School: UW Whitewater
• Department: Biological Sciences
• Course: BIOLOGY 141
• Professor: Daryle Waechter- Brulla

Document Summary

Deletion of 3 nucleotides (one amino acid) Results in: abnormal secretions in the lungs, liver, pancreas, and other glands. Insertion or deletion of 1 or 2 bases results in disruption/shifting of the reading frame. Dna ligase seals breaks in the sugar-phosphate backbone. Mismatch repair single mispaired base repaired by removing and replacing a dna segment. Base excision repair incorrect base and its sugar excised from the strand, then replaced. Nucleotide excision repair recognizes multiple mismatched bases in a region. Copy number variation (cnv) the size of a duplicated or deleted region can include one or more complete genes. Translocation in unbalanced translocation, one large segment of a chromosome is present in three copies and a large segment in the three copies and a large segment of a different chromosome is present in only one copy. 1 trait, 2 alleles (1 dominant, 1 recessive) 2 traits, each with 2 alleles (1 dominant, 1 recessive) Genes and traits do not travel together.