INTE 398 Chapter Notes - Chapter 2.10: Lazarus Syndrome, Vertically Transmitted Infection, Pharmaceutical Industry
22 Jan 2017
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Document Summary
Following timeline shows how 6. 6 million people are accessing live-saving antiretroviral therapy today. Progress due to the leadership & commitment of governments, civil society organizations and, above all, exceptional individuals. 1987 first significant step to responding to hiv: azt used to prevent hiv replication among people living with hiv. 1993 studies show no delay in progression to aids with single azt drug, debate continues about efficacy of azt. 1996 - in vancouver, researched announce a 3 drug cocktail that reduces viral load and prevents resistance which can occur with single drug therapy. This gives new hope in the community. A year later scientist find hiv hides in reservoirs, making it impossible to totally eliminate with current therapies. High income countries; rapid uptake of antiretroviral therapy rises the lazarus syndrome, with treatment can almost miraculously restore the health of people with aids but is very expensive. Large populations outside high-income countries cannot possible start and stay on these drugs.
