BIOLOGY 3UU3 Chapter Notes - Chapter 8: Slow-Wave Sleep, Cortical Column, Biological Neural Network

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Sleep function: toward elucidating an enigma (article 8) James m. krueger, marcos g. frank, jonathan p. wisor, sandip roy. Perspectives on sleep no single measure but many features can be monitored to define states of arousal able to identify sleep when correlating >>2 physiological and behavioural variables. Atp, interleukin-1 beta (il1) and tnf application of tnf to cultures induces a more intense sleep state. Acpb), the cells fail to respond to electrical stimulation by decreasing slow wave synchronization or delta power as do cells from wild type mice. Acpb knockout mice sleep less after sleep deprivation (instead of more in wt mice) 2 different popular ideas of sleep function derived from the issue of whether sleep serves a function related to small networks vs individual cells. 2 theories- connectivity theory vs cellular theory: connectivity theory network theory that involves synapses between >>2 cells.

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