EPID 301 Chapter Notes - Chapter 11: Temporality, Rare Disease, Congenital Hypothyroidism

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Case-control studies usually have analytic goals (aim to evaluate hypotheses about disease etiology- what causes disease) Some case studies have descriptive aims: to generate hypotheses. Case-control studies differ from cross-sectional studies in their selection of research participants. In case-control studies, participants are selected based on their disease status. Cross-sectional studies aim for simple random samples (each person in the population has an equal probability of selection) or probability samples (where each person has a known probability of selection) Case-control studies really have 2 processes of selection, because they select 2 groups: a group of cases and group of controls. Case-control studies cannot estimate the frequency of disease (focus on associations between risk factors and disease) Case-control studies involve identifying a set of cases (people who have a disease under investigation) and a set of controls (people who do not). Assessment of exposure in case-control studies is retrospective, because people in the (cid:281)case(cid:282) group already have the disease under investigation.

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