PHAR 100 Chapter Notes - Chapter 5: Heart Failure, Diazepam, Bioavailability

• School: Queen's University
• Department: Pharmacology and Toxicology
• Course: PHAR 100
• Professor: Bill Racz

Document Summary

Lesson a. 5 drug absorption, distribution, metabolism and excretion. Describe the mechanisms whereby drugs are absorbed by inhalation and by the mouth (oral route) Describe the procedure involved in providing a name for a new drug and provide an explanation of the terms generic and brand names. Describe the mechanisms available for termination of drug action. Describe and give examples of drug interaction. Rectal administration: used when a patient is nauseous or vomiting and therefore cannot take the drug orally or for local relief (ie. hemorrhoids, absorption of the drug occurs directly from the rectum to the blood stream. Disintegration time varies between the test tube and within body fluids. Various companies will combine different additives into the tablets influencing the activity of them within the body. Bioavailability the percentage of a drug contained in a drug product that enters the systemic (general) circulation in an unchanged form after administration of the product (includes rate of entry)