BISC 202 Chapter Notes - Chapter 13: Ribonucleotide, Start Codon, Ribosomal Rna
Document Summary
13. 1 reading notes: the genetic code uses ribonucleotide bases as letters . General features characterizing the genetic code: written in linear form letters = bases in ribonucleotides that compose mrna molecules, word = three ribonucleotide letters (triplet code), each group of three ribonucleotides is called a codon. A single coding dictionary is used by almost all viruses, bacteria, archaea and eukaryotes. 13. 2: early studies established the basic operational patterns of the code. Ribosomal rna is extremely unstable and since the intermediate that transfers genetic information from dna to proteins is extremely unstable, the intermediate must be mrna. Gain or loss of 1 or 2 nucleotides causes a frameshift, but the gain or loss of three nucleotides simply re-establishes the reading frame. 13. 3: studies by nirenberg, matthaei, and others led to deciphering of the code. Nirenberg and matthaei were the first to link specific coding sequences to specific amino acids.