LING 415 Chapter 2: D2 - Functional Magnetic Resonance Imaging (fMRI)
18 May 2019
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Ling 415 d2 - functional magnetic resonance imaging (fmri) Mris are a widely used non-invasive technique that was first used 20 years ago. Allows for brain scans in vivo (aka live) Early research suggested that the amount of blood supply that a given brain structure uses changes with the amount of activation. Early studies also showed that hemoglobin in the blood has different magnetic properties depending on whether it is attached to oxygen. Based on sensitivity to the amount of oxygen in the brain. Differences in the type of hemoglobin/blood oxygenation in the brain provide a potential intrinsic contrast mechanism (i. e. a change in mri signal sensitive to blood oxygenation) The nature of the fmri signal fmris do not directly measure neural activity. The fmri signal is commonly called the bold signal: blood oxygenation level dependent. 1) increase in bold signal is treated as brain activation, but this is based on inference.
