BIOL 1050H Chapter Notes - Chapter 7: Osteogenesis Imperfecta, Disfigurement, Calcitriol
6 Dec 2016
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7. 1 tissues and organs of the skeletal system. Acid - base balance (protects against excessive changes - absorbs or releases alkaline phosphate and carbonate salts) Matric is hardened by deposition of phosphate and other minerals. Ie. bones of the limbs (humerus, radius, metacarpals, etc) In cranium, spongy bone in enclosed between two layers of compact bone. Nutrient foramina (holes where blood vessels penetrate to bone) Perforating fibers (collagen fibers that penetrate into bone matrix) Stem cells that develop from embryonic mesenchymal cells. Single layer on the bone surface under the endosteum and periosteum. Generated is by mitosis and differentiation of osteogenic cells. Synthesize soft organic matter of the bone matrix. Osteoblasts that become trapped in matrix they deposited residing in cavities called lacunae interconnected by channels called canaliculi. Some reabsorb bone matrix and others deposit it. Contribute to maintenance of bone density and blood concentrations (calcium and phosphate)
