NURS 116 Chapter Notes - Chapter 0: Vesicoureteral Reflux, Urinary Retention, Human Microbiota
9 Mar 2019
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Document Summary
Uuti: more serious bc of ability to cause renal damage, pyelonephritis. Infection facilitated by host conditions that disrupt washout of agent from ut (urine flow, mucin lining protection, normal flora, is) Virulence of agent is derived from ability to gain access to and thrive in ut env, adhere to tissues, evade host"s is, dvlpt resistance to antimicrobials. Most uti caused by bacteria enter thru urethra; or bc of ic and neonates. Urine usually sterile washout phenomenon: urine washes bacteria out of urethra. Risk: urinary obstruction and reflux (causes urine to remain in bladder as a medium for microbial growth), sexually active women, catheters, diabetes. Host defenses: washout phenomenon, bladder lining, ir, peristalsis in ureters, iga, phagocytic blood cells, normal flora (lactobacillus), prostate secretions. Obstruction and reflux: stones, prostatic hyperplasia, pregnancy, Reflux: urine from urethra moves into bladder. Urethrovesical reflux : i ncrease in intra-abd pressure causes urine to be squeezed into urethra and flow back into bladder as pressure decreases.
