PSYCO275 Chapter 4: PSYCO 275 Ch 4.docx
21 Apr 2014
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Small group of cells called the substantia nigra were dying. These cells make dopamine, and deliver it to the striatum (part of the basal ganglia, caudate + putamen) Membrane potential: difference in electrical charge between the inside and outside of a cell: resting potential is around -70 mv (inside of neuron is negative with respect to outside, neuron membrane is polarized . Recording membrane potential: use of microelectrodes. Factors contributing to the even distribution on ions: random motion like diffusion and moving down concentration gradients, electrostatic pressure: accumulation of charges get dispersed by repulsion to like charges or. In resting neurons, k+ and cl- pass more easily through membrane than na+ and a- don"t pass through at all attraction of opposite charges. Factors contributing to uneven distribution of ions: selective permeability to certain ion (passive, sodium potassium pump: always at work. 3 na+ out for every 2 k+ in.
