BIOL 1090 Chapter Notes -Integral Membrane Protein, Electrochemical Gradient, Endoplasmic Reticulum

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12 Feb 2013
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A cell containing distinct plasma membrane domains (i. e, apical, lateral, basal) Yes different regions of the plasma membrane contain distinct proteins. Some regions (dendrites) contain proteins involved in receiving incoming signals. Other regions (terminal knobs) contain proteins involved in transmitting signals to target cells. Other regions (axon) conduct impulses away from the cell body: define active transport. Transport of a substance against its gradient the process by which a substance binds to a transmembrane protein to allow the movement of a substance against its electrochemical gradient using energy. The dopamine transporter is responsible for the reuptake of dopamine from the synapse. It clears the dopamine from the synapse by pumping it back into the neuron (using active transport) Dopamine transporter is an integral membrane protein with 12 transmembrane domains. The dopamine is moved into the cell against its concentration gradient thus energy is required to move it across. Reuptake of dopamine by the dopamine transporter is active transport.

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